1543 – The transition in cosmology from a Ptolemaic to Copernican cosmology.
1543 – The acceptance of the work of Andreas Vesalius, whose work De humani corporis fabrica corrected the numerous errors in the previously-held system created by Galen.
1687 – The transition in mechanics from Aristotelian mechanics to classical mechanics.
1783 – The acceptance of Lavoisier's theory of chemical reactions and combustion in place of
phlogiston theory, known as the chemical revolution.
1790s – The transition in optics from geometrical optics to physical optics with Augustin-Jean Fresnel's wave theory.
1826 – The discovery of hyperbolic geometry by Nikolai Lobachevsky.
1859 – The revolution in evolution from transmutation theory to goal-directed change to Charles Darwin's natural selection.
1880 - The germ theory of disease began overtaking Galen's miasma theory.
1905 – The development of quantum mechanics, which replaced classical mechanics at microscopic scales.
1887 to 1905 – The transition from the luminiferous aether present in space to electromagnetic radiation in space/time.
1919 – The transition between the worldview of Newtonian gravity and general relativity.
1964 - The discovery of cosmic microwave background radiation leads to the big bang theory being accepted over the steady state theory in cosmology.
1965 - The acceptance of plate tectonics as the explanation for large-scale geologic changes.
1974 - The November Revolution, with the discovery of the J/psi meson, and the acceptance of the existence of quarks and the Standard Model of particle physics.
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